Eddie Van Halen, the co-founder of the iconic rock band Van Halen, died on Tuesday morning after battling with throat cancer for more than 10 years. The legendary guitarist was 65.

Van Halen had a rapid decline in health in three days, a source close to him told PEOPLE. The insider said the guitar hero's health decline because the cancer cells had "spread to all his organs."

Van Halen's wife Janie Liszewski, ex-wife Valerie Bertinelli, and son Wolf were with him at the hospital during his death. Wolf confirmed the sad news on Twitter.

"I can't believe I'm having to write this, but my father, Edward Lodewijk Van Halen, has lost his long and arduous battle with cancer this morning. He was the best father I could ask for. Every moment I've shared with him on and off stage was a gift," Wolf tweeted.

The emotional tweet continued, and Wolf added: "My heart is broken, and I don't think I'll ever recover from this loss. I love you so much, Pop."

Bertinelli, Wolf's mother, replied to his son's tweet with several broken heart emojis. Van Halen was married to Bertinelli for 20 years.

Van Halen's former bandmate David Lee Roth told the Las Vegas-Review Journal earlier this year that the guitar god was not doing well as he battles with cancer.

As per the TMZ, Van Halen died at St. John's Hospital in Santa Monica.

The guitar hero has defeated tongue cancer after a two-year battle in 2002. In 2019, he was admitted to a hospital due to intestinal problems after a lousy cancer treatment reaction.

Van Halen had an interview with The Hard Times last month amid his cancer battle. The talk delved into his close relationship with his now 29-year-old son.

The iconic guitarist said there were some early signs about his son becoming a bassist. Van Halen shared that when Wolf was about nine months old, he put a little guitar in front of him, and Wolf strum the strings one at a time using his index and middle fingers instead of his thumb like a pick.

"I almost cried seeing my boy touch his first guitar. He looked so lame," he added.

Born in the Netherlands in 1955, Van Halen was raised in Pasadena, California, where he founded the band with his brother Alex in 1972.

Since then, the band has released 12 studio albums, including their latest "A Different Kind of Truth" in 2012.

Van Halen, the band, is one of the top 20 best-selling artists of all time, as per PEOPLE. It was also inducted into the Rock and Roll Hall of Fame in 2007.

Check these out:

Actor Thomas Jefferson Byrd, 70, Fatally Shot in Atlanta

Chrissy Teigen, John Legend Share Heartbreak of Losing 3rd Baby After Miscarriage

Naya Rivera's Ex Ryan Dorsey, Sister Nickayla Move in Together to Help Raise Her Son