New spoilers reveal that Stefan and Caroline may finally hook up, while a major character will die when "The Vampire Diaries" returns with new episodes starting Jan. 22.

During the epic midseason finale, Kai captured Elena after he gained access to magic while Sheriff Liz Forbes was diagnosed with cancer.

Once the show returns from its winter hiatus, Caroline will struggle to cope with the fact that her mother has a chronic disease. As a result, she will take a road trip with Stefan in hope of finding a cure for her mother. In turn, this will give the longtime friends an opportunity to spend more time with each other, which may take their friendship to the next level.

"What we'll come to see is that their relationship will be shaped by [her mom's illness]," executive producer Caroline Dries teased according to TVLine.

In the meantime, Bonnie will finally return to the present day with a brand new "bad--s" attitude.

"She's learning to put herself first," executive producer Julie Plec said, adding that Bonnie's boyfriend will also undergo a major change. "Jeremy needs to figure out what he wants out of life, and that journey will be kickstarted by the realization that he's in his own prison."

That may explain why Jeremy will decided to apply for art school, notes Wet Paint.

In addition, TVLine also lists other spoilers that fans can expect.

"Enzo will fall in lust, a set of twins will merge, 24's Annie Wersching recurs as a 'caustic' mystery lady and a major character will die," the site reports.

According to Carter Matt, the official synopsis for the upcoming episode, "Woke Up With A Monster," reads as follows:

"More powerful than ever, Kai (guest star Chris Wood) holds Elena (Nina Dobrev) captive while he learns to control his newly acquired magic. At the Salvatore mansion, Liv (guest star Penelope Mitchell) and Alaric (Matt Davis) try to prepare Jo (guest star Jodi Lyn O'Keefe) for the impending merge ceremony with Kai, but they quickly realize Jo is weaker than they thought.

"After bringing Sheriff Forbes (guest star Marguerite MacIntyre) home from the hospital, Caroline (Candice Accola) travels with Stefan (Paul Wesley) to North Carolina in search of a cure for her mother's cancer. Meanwhile, Stefan, who has his own intentions for traveling to North Carolina, is caught off guard when Enzo (Michael Malarkey) shows up demanding to know what Stefan is hiding.

"Lastly, when Damon (Ian Somerhalder) discovers Elena has been kidnapped by Kai, he is forced to rethink his strategy after an unexpected visitor throws a wrench into his plan."

Season 6, Episode 11 of "The Vampire Diaries," titled "Woke Up With a Monster," will air Thursday, Jan. 22 at 8 p.m. ET on The CW.