Several couples will face a new set of challenges when "Bones" returns from its winter hiatus later this year.

In a recent interview with TVLine, actor T.J. Thyne revealed that his character, Jack Hodgins, and Angela, played by Michaela Conlin, will face "a good amount of conflicts" in their relationship when the topic of spirituality vs. science comes up. The issue will arise after resident psychic Avalon Harmonia, played by returning guest star Cyndi Lauper, makes contact with the spirt of the late Dr. Sweets, reports TVLine.

"It's an artist and a scientist making a life together," Conlin said. "That will always bring up some issues."

Meanwhile, Cam and Arastoo will come to a crossroads when Arastoo decides to go back to Iran to take care of his brother and ends up as a political prisoner.

"He goes back because his brother is dying. That will come back in a very, very major way later on in the season," executive producer Stephen Nathan told TV Guide. "The only way he can leave is to solve a particularly sensitive murder, and of course he can't do it without help."

In addition, Brennan and Booth will face a new challenge when they try to keep Brennan's second pregnancy a secret from their coworkers, reports TVLine.

Actress Emily Deschanel also teased that fans can look forward to "a possible serial killer" in upcoming episodes.

Last month, TVLine announced that "Bones" would incorporate Deschanel's real-life pregnancy into the show.

"We are so happy for Emily," Nathan said in a statement. "As before, rather than try to hide this from a sophisticated audience, we are integrating her pregnancy into the show. Booth and Brennan, like most couples today, will continue to work, play and catch murderers -- maybe they're unique in this respect -- as their family grows. As with most new situations that have arisen in 10 years, we feel that this can only enhance the show. Although I'm sure there will be a vocal group of fans eager to attack me, I hope they will be pleasantly surprised by what we have in store."

According to Carter Matt, "Bones" the next all-new episode is scheduled for Thursday, March 26 on Fox.