After making five films together, Martin Scorsese and Leonardo DiCaprio are slated to make another one, this time a horror flick. The veteran Hollywood duo, who are know for making classic American films, have come together for an adaptation of Erik Larson novel, "The Devil in the White City," as reported by Deadline.

The film is a true story about the world's most prolific documented serial killer, Dr. H.H. Holmes.

It takes place in the 19th century, when Holmes constructed a hotel in Chicago during the World's Fair of 1893. It was to this hotel, later known as his "Murder Castle," where he would eventually lure in unsuspecting women. He would then rip them apart and sell their body parts to the medical and scientific community for research and advancement.

His torture rooms included dissecting tables, a crematorium and a gas chamber. Holmes would not only murder his victims, but he would tear them apart. He would dissect their limbs and carefully strip their skeletons. By all accounts, he was a sociopath.

In modern times, he could be compared to the fictional Thomas Harris character Hannibal Lecter. The only difference being that he was a real-life person.

Although DiCaprio is not know to take on roles like this, he has had a few that portrayed him as an anti-hero of sorts. In "Django Unchained," his character was a cunning man full of greed and based out of evil.

Scorsese has been known to make films off all different genres, but it was the mob films that gave him most of his notoriety. Those films included a multitude of scenes featuring gratuitous violence that most say were true to life. His works include "Goodfellas," "Casino" and "The Departed."

DiCaprio and Scorsese have made five films together, including "Gangs Of New York," "The Aviator," "The Departed," "Shutter Island" and "The Wolf Of Wall Street."