Vice President Biden talked openly about his apprehension about running in the 2016 presidential election and the tragic loss of his son Beau this past spring during an emotional interview on "The Late Show with Stephen Colbert" Thursday.

Biden's appearance on "The Late Show" marked the first time he has given an interview since Beau died from cancer in May. When asked to talk about his late son, the 72-year-old official remembered him for his strength and empathetic heart. Biden also admitted the attention he was receiving in wake of his loss was "a little embarrassing" for him.

"So many people who have losses as severe or maybe worse than mine and don't have the support I have," he said. "I feel self-conscious. The loss is serious and it's consequential, but there are so many other people going through this."

He went on to say his faith helped him cope with the recent loss of his son, and the loss of his first wife and daughter back in 1972. He added he feels compelled to "just get up" in order to not let Beau or his family down.

"I marvel at the ability of people who absorb hurt and just get back up," Biden said.

The VP also spoke candidly about his inhibitions about running for the presidential Democratic nomination, admitting he may not be emotionally prepared for the job.

"I don't think any man or woman should run for president unless, No. 1, they know exactly why they would want to be president, and 2, they can look at folks out there and say I promise you have my whole heart, my whole soul, my energy, and my passion," Biden said. "And, and, I'd be lying if I said that I knew I was there. I'm being completely honest. Nobody has a right in my view to seek that office unless they are willing to give it 110 percent of who they are."

At another point during the interview, when Biden hinted that he may run, the crowd began to chant "Joe! Joe! Joe!" In response, Biden laughed it off, telling the audience, "Be careful what you wish for!"

Watch the interview below.