After experiencing an alarmingly warm Christmas in New England, it looks like Old Man Winter will finally shake things up in the Northeast. Millions of Americans in certain parts of the Mid-Atlantic and Northeast could be buried with up to two feet of snow this weekend.

"Winter is ramping up," said Weather Channel lead meteorologist Kevin Roth, according to NBC News. "For many areas this will be the biggest snowfall of the season so far, and for some it could be the biggest they will have all year. It will be significant."

Forecasters say major cities on the East Coast, including Washington, D.C., Baltimore and Philadelphia, could be hit with a foot of snow or more, which will arrive on Friday or Saturday. However, it's still too early for forecasting models to predict exactly which areas will be hit the hardest and when it will happen.

"But the Northeast is not off the hook yet," Roth said. "It could shift northward more towards New England later this week." He also said that, "of the two longer-range models, one has it being heavy snow on Friday night then tapering off into Saturday, the other has it heavy on Saturday tapering off into Sunday so there are minor timing differences."

As of now, the system is just starting to head east from the Pacific and weather experts are unsure if Boston and New York will be hit by more rain or more snow. However, the mountains of Virginia, West Virginia, Maryland and Pennsylvania are likely to get up to 2 feet of snow.

"There is a moderate threat for a significant winter storm Friday into Saturday," according to the National Weather Service. It could make a mess of things from eastern Tennessee to Maine and into Canada.

In addition, meteorologist Bill Karins points out that a full moon could also cause flooding in coastal regions in the East as well.

In the meantime, those in Midwest to the East Coast have been hit with brutally cold temperatures that stretch all the way to northern Florida.