Bacterias are more harmful to human and animal bodies than most of the other dangerous elements living on earth. And among all kinds of bacteria, multi-resistant ones are perhaps the most powerful and can cause slow and immense destruction to body parts. However, to beat all these destructive beings, Multi-resistant bacteria Scientists around the world are working hard since decades. A recent finding even hinted that even certain sensitive bacteria often manage to survive antibiotic treatment as so-called 'persister cells'.

According to Science Daily, the finding was revealed by the BASP Centre, Department of Biology of the University of Copenhagen. The study was majorly focused on a newly discovered molecular mechanisms explaining how certain powerful bacteria manage to survive antibiotic treatment and cause chronic and recurrent infections. A group of scientists led by Alexander Harms examined certain substances and thereby steered the findings for implementing their focus in this study.

As per report by EurekaAlert, Harms also stated: "This amazing resilience is often due to hibernation in a physiological state called persistence where the bacteria are tolerant to multiple antibiotics and other stressors. Bacterial cells can switch into persistence by activating dedicated physiological programs that literally pull the plug of important cellular processes. Once they are persisters, the bacteria may sit through even long-lasting antibiotic therapy and can resuscitate to cause relapsing infections at any time after the treatment is abandoned."

Using novel detection methods as shown in the figure, recent work in the field has uncovered the molecular architecture of several cellular pathways underlying the formation of bacterial persisters. These results further confirmed the long-standing notion that persistence is intimately connected to slow growth or dormancy. Bacterial persistence can, therefore, be compared to hibernation of animals or the durable spores produced by many mushrooms and plants.

According to numerous potential sources the study lead by the BASP was also meant to support the development of advanced drug treatment and improved antibiotics which can overpower these terrible bacteria and destroy them forever.

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