Malaria is a life-threatening disease that brought by parasites that are transmitted to individuals through the bites of contaminated female Anopheles mosquitoes. Mosquito-borne malaria consistently infects more than 200 million individuals worldwide and kills half a million of kids in Africa. Tons of test shows conceivable new strategy for a vaccine which the researchers contaminated lab mosquitoes that are genetically weakened malaria parasites and enlisted volunteers who are willing to be bitten.

According to The Washington Post, it is a huge challenge to make individuals vaccinated using living malaria parasites that are too weak just to make people debilitated. With this study, it shows an urgent journey for an intense malaria antibody. By the year 2018, the World Health Organization is planning to extend in Africa to take a test if the initial protection which is bed netting and insecticides had been offering enough advantage for widespread use.

There is an approach that has long worked with these viruses, which desires for an exceptional protection when a Seattle team is making an immunization with entire living yet debilitated parasites. To start with, the researchers from Fred Hutchinson Cancer Researcher Center and the Center for Infectious Diseases Research expelled the three genes of malaria parasites that are basically critical to human infection. They vaccinated ten healthy volunteers not with a needle but with the captive insects for 10 minutes and every volunteer held out an arm that bitten 150 to 200 bites.

STAT reported that Dr. James Kublin, a Fred Hutchinson researcher said that they do not know how malaria parasites develop in the outside of a mosquito's salivary glands. If this approach works out, one obstacle will be getting those parasites into a conventional shot. The researchers reported in the journal Science Translational Medicine that none of the volunteers got to distinctly become sick with malaria, despite the bites brought some swelling and itching.

Later this year, the Seattle team will be going to test whether a small number of individuals that is given the genetically weakened parasites were truly secured when they are bitten by the mosquitos that convey regular malaria. Dr. Ashley Birkett, an executive of PATH's Malaria Vaccine Initiative, advised that it is too early to know the outcome of the genetically engineered parasites with a feasible approach. However, the Biotechnology company Sanaria has reported promising early outcomes with a distinct method for debilitating malaria by illuminating thousands of infected mosquitoes and gathered them with the weakened parasite out of their salivary organs.