A law enforcement source informed PEOPLE that the investigation into the Matthew Perry death due to ketamine overdose is nearing completion.

Authorities are considering charges against multiple individuals, pending a decision by the US Attorney's Office.

Perry, famous for his iconic role in the TV series 'Friends,' has sadly passed away at 54 last October in what was ruled an accidental death.

His autopsy revealed that ketamine's acute effects, combined with drowning, coronary artery disease, and the impact of buprenorphine, a drug for opioid use disorder, contributed to his demise.

The Los Angeles County Medical Examiner's Office closed its investigation in December, prompting subsequent inquiries by the LAPD.

READ NEXT: Law Enforcement Probes Matthew Perry's Death with Federal Involvement 

Federal Investigation and Autopsy Findings

According to a law enforcement insider speaking to People, the federal investigation surrounding Matthew Perry's death is set to conclude soon, with decisions on potential charges imminent.

The US Attorney's Office declined to comment when approached by Page Six on June 25.

Perry's autopsy disclosed the presence of ketamine in his system, alongside other factors such as drowning and coronary artery disease.

His memoir, "Friends, Lovers, and the Big Terrible Thing," revealed his struggles with ketamine use, describing the drug's effects as overwhelming and unpleasant.

Despite the LAPD concluding its initial investigation in January, TMZ reported in May that federal authorities began probing Perry's ketamine usage.

Dr. Bankole Johnson speculated on Page Six that Perry might have obtained ketamine illegally for recreational purposes, considering his concurrent use of buprenorphine.

Perry was found dead in his Los Angeles residence's hot tub after sending his assistant on errands.

He had been transparent about his battle with substance abuse, documenting in his memoir a lifelong struggle that included spending millions on recovery efforts.

Ongoing Police and Federal Investigation

The Los Angeles Police Department confirmed to Fox News Digital that their investigation into Matthew Perry's death remains active.

Authorities are collaborating with the DEA and US Postal Inspection Service to determine the source of the ketamine found in Perry's system at the time of his death.

According to Perry's autopsy, trace amounts of ketamine were detected in his stomach. However, the exact method of ingestion remains unclear.

The autopsy also noted the presence of prescription medications and loose pills at his residence.

Ketamine, primarily used as an anesthetic, was administered to Perry through infusion therapy for depression and anxiety.

Despite his last treatment occurring over a week before his death, the autopsy ruled out that this therapy caused the fatal ketamine levels due to its short half-life.

First responders found Perry unconscious in his hot tub, already deceased upon their arrival.

His death prompted the LAPD's Robbery-Homicide Division to take over the case, which is standard procedure for high-profile investigations.

Born in Massachusetts and raised in Canada, Matthew Perry gained fame as Chandler Bing on the iconic "Friends" sitcom, which premiered in 1994 and remains a cultural touchstone.

READ MORE: Tamayo Perry, Surfer and 'Pirates of the Caribbean' Actor, Dies in Hawaii Shark Attack 

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Written by: Ross Key

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