MTV star Diem Brown was diagnosed with cancer for the third time, and though it has spread to her liver and lymph nodes, she remains optimistic.

The 33-year-old "The Challenge" contestant is known for having an on-again, off-again relationship with Chris "CT" Tamburello and for having defeated cancer. She was admitted to the hospital, and Brown said that it seems her doctors have lost hope.

"I NEED PRAyErs and advice my doctors are seemingly giving up but I won't & can't rollover. Whatever option I have to LIVE I'm grabbing!" she said on Twitter.

In her next tweet, she told people to contact E! News correspondent Alicia Quarles with "prayers, advice, support & outreach." Brown explained that she wouldn't just accept no for an answer.

Quarles has been a supportive friend throughout it all. She has posted a series of pictures of Brown in the last few days.

"I'm with @diembrown right now," she said on Tuesday. "We both believe in the power of prayer. She's asked that I ask all of you to pray for her. God is good. Diem would like a huge prayer circle. I reassured her she has one. Diem smiled and told me, a little reminder never hurts :-)"

In September, Tamburello shared a picture of himself at Brown's bedside. He said that sometimes being there for someone could improve their spirits, and he knew that Brown could use more happiness.

Since then, Tamburello has only used his Instagram to share pictures about Brown. Each of them has a link to her Medgift Support Page, which was raising money for Brown's medical bills.

His last post was on Nov. 5. It was a photo of Brown for Woman Crush Wednesday.

"Your smile can change the world. It's not the other way around... @diembrown #myly #strongereveryday," he said. "Feel free to check out her support page and help keep a smile on her face! #MedGift"