In "Grey's Anatomy" Season 12, Episode 3 "Choose You," Maggie Pierce (Kelly McCreary) reviews her life choices after receiving a wedding invitation from a former boyfriend.

Richard Webber (James Pickens, Jr.) questions Miranda Bailey's (Chandra Wilson) loyalty.

Alex Karev (Justin Chambers) has to make a difficult decision concerning the lives of newborn twins.

In the Episode 3 trailer, Jo Wilson (Camilla Luddington) confides in Stephanie Edwards (Jerrika Hinton) about a secret she's been keeping from Karev. She and Edwards are shown talking in a Grey Sloan Memorial Hospital ladies room.

"When did you find out," Edwards asks.

"This morning," Wilson says.

Edwards asks about Karev's reaction.

"I haven't talked to him yet," Wilson says, exasperated.

"You have to talk to him --"

"It's not like I wanted this to happen," Wilson says.

In the clip's next scene, Karev joins Wilson in a hospital elevator.

She's gawking at him nervously. He asks her what's wrong.

"Nothing," she assures him, but asks, "Do you want to have kids?"

Karev is caught off guard.

"Uh, I don't...know...I mean, yeah -- now?" he asks.

Wilson gets flustered and tells him it is a simple yes or no question.

"What the hell is going on?" he asks, and the clip ends.

Karev loves children. He works every day to save the lives of his young patients. Is he ready for children of his own?

Meanwhile, April Kepner (Sarah Drew) is trying to spark romance with husband Jackson Avery (Jesse Williams), but he is still coming to terms with the fact she left him. In "Choose You," the couple argues over their relationship status. He threatens to change the locks on the apartment.

Realty Today reports that Arizona Robbins (Jessica Capshaw) will find a new love interest -- a man -- during Season 12 of "Grey's Anatomy" as her ex-wife, Callie Torres (Sara Ramirez), continues to date another woman.

Watch "Grey's Anatomy" Season 12, Episode 3 "Choose You" on Thursday, Oct. 8, at 8 p.m. ET on ABC.

Do you think Karev is ready to be a father? Is Avery being too hard on Kepner for having left him to practice medicine in the Army? Share your thoughts in the comment section below.