Giuliana Rancic is reportedly outraged over her gut-wrenching belief that one-time "Fashion Police" co-host Kelly Osbourne never stood up for her during her ordeal over making derogatory remarks about Disney Star Zendaya's dreadlock-style hair.

"Kelly is dead to Giuliana," a source alleged to Us Weekly.

The two have been at odds since the night of February 23 when Rancic said that Zendaya's hair "smells like patchouli oil, or maybe weed."

Later Osbourne tweeted:

The simmering feud again came to a boil earlier this month when Rancic appeared on the "Today" show and again alleged that the Zendaya remarks did not come directly from her. Instead, she said they were scripted by a writer.

The same day, Osbourne dismissively tweeted, "Liars always get caught."

A source later told to the website of the remark, "It was about Giuliana."

The two were once close, with Osbourne telling Us Magazine in 2013, "We are like family."

But after longtime show host Joan Rivers passed away last September, things quickly began to sour. A friend of Osbourne later told the website the feeling was Rancic "tried too hard to be funny" in Rivers' absence. Another source added of their supposedly faltering relationship, "They didn't see eye to eye on what was funny versus offensive."

Back in March, Rivers' replacement, Kathy Griffin, abruptly quit the show and sources told RadarOnline, "Everyone just feels like 'Fashion Police' is a sinking-ship and Giuliana Rancic is the anchor."

At that time, network execs were also rumored to be considering pulling the plug on the entire operation.

"Kathy and Kelly both felt like Joan would not have wanted the show to go on like this," the RadarOnline source added. "A lot of people think E! should just let Joan's chair be her chair forever and pull the plug on the show while they are ahead."