Manchester United will look to score their second victory, while powerhouse clubs Chelsea and Manchester City will collide in Week 2 of the 2015-16 English Premier League season.

Manchester United, who will face Aston Villa on Friday, had a slow start during their season opener last week, but they managed to escape with a 1-0 win over the Tottenham Hotspur, off an own goal from Kyle Walker during the 22nd minute of the match.

On the other hand, Aston Villa opened their season with a 1-0 win against AFC Bournemouth off a goal from substitute Rudy Gestede, who is expected to come off the bench again on Friday.

Aston Villa will look to a start the season with two consecutive wins, but they need to do it without injured Jack Grealish, Carles Gil and Jokes Okore.

Manchester United will play without top goalkeeper David De Gea again, while Red Devils manager Louis van Gaal also confirmed that Phil Jones and Marcus Rojo will not be available on Friday.

Van Gaal told MUTV that Jones is still recovering from an illness, while Rojo needs more time to get into his rhythm after a busy offseason with the Argentina national soccer team.

Meanwhile, defending champions Chelsea will look to score their first win of the season. The Blues settled for a 2-2 draw during their opener against Swansea City at Stamford Bridge.

Chelsea's defense will have to step up, though, as they will miss top goalkeeper Thibaut Courtois, who was suspended after getting a red card last week.

On the other hand, Sergio Aguero is expected to suit up again, but it remains to be seen whether or not he will start for Manchester City, who opened their season with a 3-0 win against West Bromwich Albion on Monday.

English Premier League 2015-16 Season Week 2 Schedule

Friday - August 14

  • Aston Villa vs. Manchester United - 2:45 p.m. ET

Saturday - August 15

  • Southampton vs. Everton - 7:45 a.m. ET
  • Sunderland vs. Norwich City - 10 a.m. ET
  • Swansea City vs. Newcastle United - 10 a.m. ET
  • Tottenham Hotspur vs. Stoke City - 10 a.m. ET
  • Watford vs. West Bromwich Albion - 10 a.m. ET
  • West Ham United vs. Leicester City - 10 a.m. ET

Sunday - August 16

  • Crystal Palace vs. Arsenal - 8:30 a.m. ET
  • Manchester City vs. Chelsea - 11:00 a.m. ET

Monday - August 17

  • Liverpool vs. AFC Bournemouth - 3:00 p.m. ET

TV schedule and streaming information are available on this link from Live Soccer TV. The updated 2015-16 EPL Season league table can be seen on this link.

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