Tournament favorites Novak Djokovic and Serena Williams will resume their campaign on Day 7 of the 2015 US Open Tennis at Flushing Meadows in New York.

Djokovic, the top-seeded player in the men's draw, will face 23rd seed Roberto Bautista Agut of Spain on Sunday night at Arthur Ashe Stadium.

Djokovic, who is looking to win just the second US Open title of his career, is a heavy favorite heading into the showdown after not dropping a single set in his first three matches.

The nine-time Grand Slam champion kicked off his campaign with a 6-1, 6-1, 6-1 win in the opening round, which was followed by a 6-4, 6-1, 6-2 win against Andreas Haider-Maurer. In the third round, Djokovic was challenged, but he still managed to run away with a 6-3, 7-5, 7-5 win against 25th seed Andreas Seppi.

On the other hand, Agut earned a spot in the second round of the tournament after 14th seed David Goffin of Belgium failed to continue during their match, which ended 2-6, 5-7, 6-3, 3-1.

In other notable matches, defending champion Marin Cilic will try to advance to the quarterfinals. The ninth seed will go up against 27th seed Jeremy Chardy of France in the opening game at the Arthur Ashe Stadium.

Fabio Fognini of Italy, who pulled off a huge upset win against 14-time Grand Slam champion Rafael Nadal in the third round, will collide with 18th seed Feliciano Lopez of Spain.

In the women's side, top seed and defending champion Serena Williams will try to bounce back from an inconsistent showing during her third-round assignment.

Williams, who has won all Grand Slam titles this year, will face 19th seed compatriot Madison Keys -- two days after the 33-year-old superstar almost took an early exit before escaping with a come-from-behind 3-6, 7-5, 6-0 win against Bethanie Mattek-Sands.

Williams, who is also eyeing her fourth consecutive Grand Slam titles at Flushing Meadows, is hoping she will play better against Keys compared to her performance against Mattek-Sands.

"I think that she played a really high-intensity match," Williams said of Keys. "I thought she served really well. I served well. So hopefully I'll be able to show up and play well. We'll see."

Complete 2015 US Open Day 7 schedule and match times can be seen on the tournament's official website. Fans can watch the matches on ESPN and through online streaming via US Open Live and WatchESPN.